New Key Found To Decipher Triple-Negative Breast Cancer

New studies conducted have suggested evidence that scanning a breast cancer patient for prolactin receptors can help physicians to improve the prognosis of their patients. It is also possible to use this information to prevent a needless treatment which may be invasive. The study was conducted at the Institute for Research at the McGill University Health Center.

  • 580 patients were scanned in the study: A data set consisting of five hundred and eighty women was considered. All these women suffered from triple negative breast cancer (TNBC), which is basically a kind of tumor that is very aggressive and difficult to provide treatment for. The tumor itself is negative to estrogen receptors, progesterone receptors, as well as negative for HER2.
  • Limited treatment options for TNBC cancers: Most treatment options available for these patients are either highly invasive, such as chemotherapy, and even after treatment, the prognosis is rather grim for these patients. This is because each TNBC cancer is unique and their behavior differs from woman to woman.
  • Women with the prolactin receptor had the least aggressive breast cancer: In a pre clinical test model, scientists worked out that in cases where prolactin receptors were present; the cells of the tumor were less aggressive, as well as less likely to proliferate and invade the patient’s body. Women who had a tumor with the receptors had a significantly better prognosis on the whole, and their cancer was easier to contend with.

Despite the effects of prolactin in breast cancers not being solidly known, this study has proved that an improved study of it can significantly improve a physician’s ability to help their patients. The research has also supported the notion that breast feeding is of benefit to both the child and mother- to the latter by supposedly suppressing breast cancer, thanks to breast cancer producing higher prolactin levels. A more in-depth study is needed to prove these facts.


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